ANTIDIABETIC ACTIVITY OF LEAF OF HIBISCUS MUTABILIS (Cotton rosemallow)

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ANTIDIABETIC ACTIVITY OF LEAF OF HIBISCUS MUTABILIS


Hibiscus mutabilis L. is an inland woody shrub up to 1.5-4.0 m tall and it is native to China and widely cultivated in Southeast Asia as an ornamental plant for its beautiful flower [1]. H. mutabilis is belonging to family Malvaceae and commonly known as changeable rose or Cotton rosemallow, Dixie rosemallow, Confederate rose, Sthalkamal or Sthalpadma [2-3]. Leaves of H. mutabilis are broadly ovate with mostly five triangular lobes. H. mutabilis creates large and beautiful flowers and Flower colour change in H. mutabilis is most spectacular. The flowers are of three different colors seem on the bush instantaneously as the blooms color cycle self-regulating of one another. Colours of the Flowers are white in the morning, pink in the afternoon, and red in the evening. MORE DETAILS AND IMAGES

Das et al 2013 from Department of Pharmacology, Malhotra College of Pharmacy, Bhopal, Madhya Pradesh, India investigated anti-diabetic activity of methanolic extract of leaf of Hibiscus mutabilis (Malvaceae) in alloxan induced diabetes wistar rats and compared with standard. The results of this study described that Methanolic extract has significant protection and maximum reduction in glucose in alloxan induced diabetes wistar rats. As per the investigation maximum reduction in glucose was observed after 6 hours at a dose level of 200 mg/kg of body weight of alloxan induced diabetes wistar rats. In this study blood sugar level was determined using digital glucometer. According to this comprehensive study Hibiscus mutabilis leaf had shown statistically significant anti-diabetic activity in comparison to the standard glibenclamide. On basis of this scientific investigation we can use the leaf of Hibiscus mutabilis as a natural remedy for diabetics.

Reference

• Sattwik Das, Shailendra Lariya and Girendra Kumar Gautam. Antidiabetic Activity of Methanolic Extract of Hibiscus Mutabilis Leaves Against Alloxan Induced Diabetes in Rats. International journal of pharmaceutical and chemical sciences, Vol. 2 (3) Jul-Sep 2013.

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